Post-Doctoral Fellow - Principal Investigator
| Address | Department of Medicine 2 |
|---|---|
| Hematology/Oncology | |
| University Hospital Frankfurt | |
| Goethe University | |
| Theodor-Stern-Kai 7 | |
| Hs25A, Rm313 | |
| 60590 Frankfurt am Main | |
| E-Mail: | kurrle@med.uni-frankfurt.de |
| Degrees | PhD (2014), Goethe University Frankfurt, Germany |
| Diploma degree biology (2008), Goethe University Frankfurt, Germany | |
| Postgraduate diploma (2005), University of Otago, New Zealand |
Expertise and interests
I was trained as a biochemist and cellular biologist. During my PhD, my research focused on molecular mechanisms involved in cell signaling, cell-cell and cell-matrix adhesion. In September 2013, I joined the department of Hematology/Oncology as a Post-Doc in a research project within the SFB815 (redox regulation) under supervision of Prof. Harald von Melchner and Prof. Hubert Serve focusing on the redox-sensitive regulation of mTORC1- and receptor tyrosine kinase-signaling by sestrin proteins. During this time, I gained extensive experience in the analysis of redox-dependent processes and genome-editing techniques in various cellular systems. In my current research, I focus on redox-dependent signal transduction pathways in acute myeloid leukemia (AML) and multiple myeloma (MM) with emphasis on bone-marrow microenvironmental cues to unravel molecular mechanisms involved in disease progression and to identify novel vulnerabilities for AML and MM treatment.
Positions held
| since 2016 | Postdoctoral Fellow, Dept. of Medicine 2, Hematology/Oncology, University Hospital Frankfurt |
|---|---|
| 2013-2016 | Postdoctoral Fellow, Molecular Hematology, University Hospital Frankfurt |
| 2009-2013 | PhD student, Institute of Biochemistry, JLU Giessen |