Dr. Nina Kurrle

Post-Doctoral Fellow - Principal Investigator 

AddressDepartment of Medicine 2
University Hospital Frankfurt
Goethe University
Theodor-Stern-Kai 7
Hs25A, Rm313
60590 Frankfurt am Main
E-Mail: kurrle@med.uni-frankfurt.de
Degrees PhD (2014), Goethe University Frankfurt, Germany
Diploma degree biology (2008), Goethe University Frankfurt, Germany
Postgraduate diploma (2005), University of Otago, New Zealand

Expertise and interests

I was trained as a biochemist and cellular biologist. During my PhD, my research focused on molecular mechanisms involved in cell signaling, cell-cell and cell-matrix adhesion. In September 2013, I joined the department of Hematology/Oncology as a Post-Doc in a research project within the SFB815 (redox regulation) under supervision of Prof. Harald von Melchner and Prof. Hubert Serve focusing on the redox-sensitive regulation of mTORC1- and receptor tyrosine kinase-signaling by sestrin proteins. During this time, I gained extensive experience in the analysis of redox-dependent processes and genome-editing techniques in various cellular systems. In my current research, I focus on redox-dependent signal transduction pathways in acute myeloid leukemia (AML) and multiple myeloma (MM) with emphasis on bone-marrow microenvironmental cues to unravel molecular mechanisms involved in disease progression and to identify novel vulnerabilities for AML and MM treatment. 

Positions held

since 2016Postdoctoral Fellow, Dept. of Medicine 2, Hematology/Oncology, University Hospital Frankfurt
2013-2016Postdoctoral Fellow, Molecular Hematology, University Hospital Frankfurt
2009-2013PhD student, Institute of Biochemistry, JLU Giessen

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