PD. Dr. Dr. Frank Schnütgen

Principal Investigator – Lab Coordinator

AddressDepartment of Medicine 2
University Hospital Frankfurt
Goethe University
Theodor-Stern-Kai 7
Hs25A, Rm302
60590 Frankfurt am Main
E-Mail: schnuetgen@em.uni-frankfurt.de
Degrees PhD (1997), Westfälische-Wilhelms-Universität Münster

Expertise and interests

I gained extensive experience in precise genome editing in eukaryotic cellular systems. At my start in Frankfurt, I developed a novel gene therapy approach based on gene trapping that circumvents genotoxicity and transgene silencing. At that time, I was responsible for vector development within the German Gene Trap Consortium (GGTC) and the European Conditional Mouse Mutagenesis (EUCOMM) program to which I contributed a large variety of different gene driven mutagenesis strategies. I was trained as a Biochemist, Molecular and Cellular Biologist. My current research focus lies in the influence of the microenvironment on leukemic cell behavior, genetic editing and genome-wide genetic screens as well as in the development of techniques for the gene therapy of monogenic diseases using the CRISPR/Cas9 technology. 

Positions held

since 2016Lab Coordinator, Dept. of Medicine 2, Hematology/Oncology, University Hospital Frankfurt
since 2008Facility Manager of Genetic Engineering
2001-2016Postdoctoral Fellow, Molecular Hematology, University Hospital Frankfurt
1998-2000Postdoctoral Fellow, IGBMC, Illkirch, Strasbourg, France
1993-1997PhD student, Dept. of Biochemistry, WWU Münster
1996Visiting Scientist, Albert-Einstein-College of Medicine, New York, USA
1993Diploma degree chemistry, WWU Münster

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