Principal Investigator – Lab Coordinator
| Address | Department of Medicine 2 |
|---|---|
| Hematology/Oncology | |
| University Hospital Frankfurt | |
| Goethe University | |
| Theodor-Stern-Kai 7 | |
| Hs25A, Rm302 | |
| 60590 Frankfurt am Main | |
| E-Mail: | schnuetgen@em.uni-frankfurt.de |
| Degrees | PhD (1997), Westfälische-Wilhelms-Universität Münster |
Expertise and interests
I gained extensive experience in precise genome editing in eukaryotic cellular systems. At my start in Frankfurt, I developed a novel gene therapy approach based on gene trapping that circumvents genotoxicity and transgene silencing. At that time, I was responsible for vector development within the German Gene Trap Consortium (GGTC) and the European Conditional Mouse Mutagenesis (EUCOMM) program to which I contributed a large variety of different gene driven mutagenesis strategies. I was trained as a Biochemist, Molecular and Cellular Biologist. My current research focus lies in the influence of the microenvironment on leukemic cell behavior, genetic editing and genome-wide genetic screens as well as in the development of techniques for the gene therapy of monogenic diseases using the CRISPR/Cas9 technology.
Positions held
| since 2016 | Lab Coordinator, Dept. of Medicine 2, Hematology/Oncology, University Hospital Frankfurt |
|---|---|
| since 2008 | Facility Manager of Genetic Engineering |
| 2001-2016 | Postdoctoral Fellow, Molecular Hematology, University Hospital Frankfurt |
| 1998-2000 | Postdoctoral Fellow, IGBMC, Illkirch, Strasbourg, France |
| 1993-1997 | PhD student, Dept. of Biochemistry, WWU Münster |
| 1996 | Visiting Scientist, Albert-Einstein-College of Medicine, New York, USA |
| 1993 | Diploma degree chemistry, WWU Münster |